Core conserved transcriptional regulatory networks define the invasive trophoblast cell lineage

Our collaborative manuscript was published in Development today! We worked with the Michael Soares group to integrate our previously published single-cell RNA-seq data generated in the rat uterine-placental interface with single-nucleus ATAC-seq data generated at the same stage and in the same tissue type. We identified chromatin accessibility profiles in different cell types and identified a conserved gene
regulatory network in invasive trophoblast cells. This work will will facilitate future studies investigating regulatory mechanisms in the invasive trophoblast cell lineage.

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