Transcription Factor PLAGL1 Is Associated with Angiogenic Gene Expression in the Placenta

An article from the Tuteja lab, "Transcription factor PLAGL1 is Associated with Angiogenic Gene Expression in the Placenta" was published in IJMS today! Rebekah Starks, PhD student in Bioinformatics and Computational Biology, is lead author on the paper. In this article, she uses computational analyses to predict PLAGL1 as an important regulator in mouse midgestation placenta. Using a series of experiments in mouse placenta and a human placenta cell line, she demonstrates that PLAGL1 is associated with Angiogenic Gene Expression, and regulates cord formation in cell culture. Thanks also to our collaborators on the project, Laura Schulz and Kathleen Pennington. Congrats, all!